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What is Esclim (Estradiol-Transdermal Biweekly) ?

Can I buy Esclim without Health Insurance, Medicare or Medicaid? Check and see if we carry Esclim in our prescription list!

What Alternate Names Are There For Esclim? Vivelle, Vivelle-Dot, Alora

How is Esclim (Estradiol-Transdermal Biweekly) Pronounced? ess-truh-DYE-all

Who is the Manufacturer of Esclim? Women First Hc

What is Esclim Used For? Esclim is a female hormone and is usually given to women who no longer produce the proper amount. It is used to reduce menopause symptoms (e.g., hot flashes, vaginal dryness), to prevent bone loss (osteoporosis) in people at high risk, and to treat other conditions as determined by your doctor. If you are only being treated for vaginal menopause symptoms, products applied locally such as vaginal creams, tablets, or rings should be considered before products taken by mouth or absorbed through the skin. There are several medications (e.g., raloxifene or bisphosphonates) that are safe and effective to prevent or treat bone loss. These medicines should be considered for use before estrogen therapy. If you have other medical conditions as well, and are prescribed estrogens for more than one condition, consult your doctor about your treatment plan and its options.

How To Use Esclim
Use Esclim exactly as prescribed. The patch is usually replaced twice a week (about every 3 to 4 days), or as directed by your doctor. Follow the dosing schedule carefully. Do not open the sealed pouch container until ready to use. Open the pouch and remove the patch from the protective liner. Apply the patch to a clean, dry, hairless area as directed by your doctor or by the patient information leaflet. This patch should only be applied to certain areas of the body. Different brands of patches are applied to different areas of the body. If you have any questions about where to apply the patch, ask your doctor or pharmacist. Press the patch firmly against the skin for about 10 seconds to make sure the patch stays on. Do not apply to a site that is exposed to sunlight and do not place the patch on the breast. Avoid applying to the waistline since tight clothing may rub the patch off. Do not put the patch on areas where sitting may loosen it. When it is time to change the patch, remove it and dispose of it properly. Apply a new patch to a different area to prevent skin irritation. It is best to rotate the areas where the patch is applied, allowing at least 1 week in between applications to the same site. If the area around the patch becomes red, itchy, or irritated, try a new site. If the irritation continues or becomes worse, notify your doctor promptly. If a patch falls off, reapply it or apply a new patch and wear it for the rest of the scheduled period. Read the Patient Information Leaflet available from your pharmacist. Consult your doctor or pharmacist if you have any questions.

Esclim Side Effects
Dizziness, lightheadedness, headache, stomach upset, bloating, nausea, weight changes, increased/decreased interest in sex, breast tenderness, or skin redness/irritation at the application site may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., severe depression, memory loss), calf pain/swelling, sudden severe headache, chest pain, trouble breathing, one-sided weakness, slurred speech, vision changes (e.g., change in contact lens fit, loss of vision), breast lumps, swelling of hands or feet, changes in vaginal bleeding (e.g., spotting, breakthrough bleeding or prolonged bleeding), unusual vaginal discharge/itching/odor, yellowing of the eyes or skin. An allergic reaction to Esclim is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Esclim Precautions
Esclim should not be used if you have certain medical conditions. Before using Esclim, consult your doctor or pharmacist if you have: undiagnosed abnormal vaginal bleeding, certain cancers (e.g., breast cancer, especially non-metastatic type), blood clots, active/recent stroke or heart attack, liver disease. Before using Esclim, tell your doctor or pharmacist your medical history, especially of: family medical history (especially breast lumps and cancer), asthma, diabetes, seizures, migraine headaches, heart disease (e.g., high blood pressure, heart attacks, congestive heart failure), kidney disease, low thyroid hormone (hypothyroidism), abnormal calcium level in the blood, depression, high blood pressure during pregnancy (toxemia), yellowing of eyes and skin (cholestatic jaundice) during pregnancy or with past estrogen use, womb problems (e.g., uterine fibroids, endometriosis), cholesterol or lipid problems, gallbladder disease, excessive weight gain, certain blood disorder (porphyria), any allergies. If you will be having surgery or will be confined to a chair or bed for a long period of time (e.g., a long plane flight), notify your doctor beforehand. Special precautions may need to be taken in these circumstances while you are taking Esclim. Esclim may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. Esclim may cause a patchy darkening of the skin on the face (melasma). Sunlight may intensify this darkening and you may need to avoid prolonged sun exposure and sunlamps. Consult your doctor regarding use of sunscreens and protective clothing. Cigarette smoking can increase the chance of blood clots while taking Esclim (especially in women over the age of 35). If Esclim is used in children, their growth pattern should be monitored as Esclim might stunt their growth. Esclim must not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. Esclim may pass into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using Esclim is not recommended.

Esclim Drug Interactions
Before using Esclim, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: corticosteroids (e.g., prednisone), hydantoins (e.g., phenytoin), warfarin. Also tell your doctor or pharmacist if you are taking any medications which affect certain liver enzymes (CYP450-3A4 enzymes), such as: azole antifungals (e.g., ketoconazole, itraconazole), carbamazepine, cimetidine, macrolide antibiotics (e.g., clarithromycin, erythromycin), phenobarbital, rifamycins (e.g., rifampin), ritonavir, St. John s wort. This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use Esclim. Do not start or stop any medicine without doctor or pharmacist approval.

Esclim Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: severe nausea/vomiting or excessive vaginal bleeding.

Missed Esclim Dose
If you miss a dose, use it as soon as you remember. If a patch falls off, reapply it or apply a new patch and wear it for the rest of the scheduled period, then resume your usual dosing schedule. Do not double the dose to catch up.

Esclim Storage
Store the sealed pouches according to the package instructions away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Generic and Namebrand Variations
Label Name	Unit	Package	Color	Shape	Flavor	NDC
Alora 0.025mg Patch	Tdp	Box	Translucent	Rectangular		52544088408
Esclim 0.025mg Patch	Tdp	Box	Translucent	Rectangular		64248031001
Vivelle 0.025mg Patch	Tdp	Packet				00078034844
Vivelle 0.025mg Patch	Tdp	Packet	Colorless	Round		00078034842
Vivelle 0.025mg Patch	Tdp	Packet	Colorless	Round		00078034862
Vivelle-Dot 0.025mg Patch		Packet	Colorless	Rectangular		54868486200
Vivelle-Dot 0.025mg Patch	Tdp	Packet	Colorless	Rectangular		00078036542
Vivelle-Dot 0.025mg Patch	Tdp	Packet	Colorless	Rectangular		00078036545

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