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What is Climara (Estradiol-Transdermal Weekly) ?

Can I buy Climara without Health Insurance, Medicare or Medicaid? Check and see if we carry Climara in our prescription list!

What Alternate Names Are There For Climara? Estradiol Transdermal Patch, Estradiol

How is Climara (Estradiol-Transdermal Weekly) Pronounced? ess-truh-DYE-all

Who is the Manufacturer of Climara? Berlex Labs.

What is Climara Used For? Climara is a female hormone and is usually given to women who no longer produce the proper amount. It is used to reduce menopause symptoms (e.g., hot flashes, vaginal dryness), to prevent bone loss (osteoporosis) in people at high risk, and to treat other conditions as determined by your doctor. If you are only being treated for vaginal menopause symptoms, products applied locally such as vaginal creams, tablets, or rings should be considered before products taken by mouth or absorbed through the skin. There are several medications (e.g., raloxifene or bisphosphonates) that are safe and effective to prevent or treat bone loss. These medicines should be considered for use before estrogen therapy. If you have other medical conditions as well and are prescribed estrogens for more than one condition, consult your doctor about your treatment plan and its options.

How To Use Climara
One patch is usually worn for 1 week and then replaced, or use as directed by your doctor. Follow the dosing schedule carefully. Do not open the sealed pouch container until ready to use. Open the pouch and remove the patch from the protective liner. Apply the patch to a clean, dry area on the lower stomach or the top of the buttocks, pressing firmly for about 10 seconds to make sure the patch stays on. Do not place the patch on the breast. Avoid applying to the waistline since tight clothing may rub the patch off. Do not put the patch on areas where sitting may loosen it. After 1 week, remove the patch and dispose of it properly. Apply a new patch to a different area to prevent skin irritation. If the area around the patch becomes red, itchy, or irritated, try a new site. If the irritation continues or becomes worse, notify your doctor promptly. If a patch falls off, reapply it or apply a new patch and wear it for the rest of the 7-day period. Read the Patient Information Leaflet available from your pharmacist. Consult your doctor or pharmacist if you have any questions.

Climara Side Effects
Dizziness, lightheadedness, headache, stomach upset, bloating, nausea, weight changes, increased/decreased interest in sex, breast tenderness, or skin redness/irritation at the application site may occur. If any of these persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., severe depression, memory loss), calf pain/swelling, sudden severe headache, chest pain, trouble breathing, one-sided weakness, slurred speech, vision changes (change in contact lens fit, loss of vision), breast lumps, swelling of hands or feet, changes in vaginal bleeding (e.g., spotting, breakthrough bleeding or prolonged bleeding), unusual vaginal discharge/itching/odor, yellowing of eyes or skin. An allergic reaction to Climara is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Climara Precautions
Climara should not be used if you have certain medical conditions. Before using Climara, consult your doctor or pharmacist if you have: undiagnosed abnormal vaginal bleeding, certain cancers (e.g., breast cancer, especially non-metastatic type), blood clots, active/recent stroke or heart attack, liver disease. Before using Climara, tell your doctor or pharmacist your medical history, especially of: family medical history (especially breast lumps and cancer), asthma, diabetes, seizures, migraine headaches, heart disease (e.g., high blood pressure, heart attacks, congestive heart failure), kidney disease, low thyroid hormone (hypothyroidism), abnormal calcium level in the blood, depression, high blood pressure during pregnancy (toxemia), yellowing of eyes and skin (cholestatic jaundice) during pregnancy or with past estrogen use, womb problems (e.g., uterine fibroids, endometriosis), cholesterol or lipid problems, gallbladder disease, excessive weight gain, certain blood disorders (porphyria), any allergies. Before having surgery or if you require prolonged bedrest, tell the doctor that you take Climara. Climara may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. Climara may cause a patchy darkening of the skin on the face (melasma). Sunlight may intensify this darkening and you may need to avoid prolonged sun exposure and sunlamps. Consult your doctor regarding the use of sunscreens and protective clothing. Cigarette smoking can increase the chance of blood clots while taking Climara (especially in women over the age of 35). If Climara is used in children, their growth pattern should be monitored as Climara might stunt their growth. Climara must not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. Climara may pass into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using Climara is not recommended.

Climara Drug Interactions
Before using Climara, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: corticosteroids (e.g., prednisone), hydantoins (e.g., phenytoin), warfarin, drugs which affect certain liver enzymes (CYP450-3A4 enzymes) such as azole antifungals (e.g., ketoconazole, itraconazole), carbamazepine, macrolides (e.g., clarithromycin, erythromycin), phenobarbital, rifamycins (e.g., rifampin), ritonavir, cimetidine, St. John s Wort. This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use Climara. Do not start or stop any medicine without doctor or pharmacist approval.

Climara Overdose
If overdose is suspected, remove the patch. Contact your local poison control center or emergency room immediately. Symptoms of overdose may include: severe nausea/vomiting or excessive vaginal bleeding.

Missed Climara Dose
If you miss a dose, use it as soon as you remember. If a patch falls off, apply a new patch and wear it for the rest of the 7-day period, then resume your usual dosing schedule. Do not double the dose to catch up.

Climara Storage
Store the sealed pouches at room temperature below 86 F (30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Generic and Namebrand Variations
Label Name	Unit	Package	Color	Shape	Flavor	NDC
Climara 0.05mg/day Patch		Box				54569471100
Climara 0.05mg/day Patch		Box				54868408900
Climara 0.05mg/day Patch	Ea	Box	Colorless	Octagonal		50419045104
Estradiol 0.05mg/day Patch		Box				54868481100
Estradiol 0.05mg/day Patch		Box	Flesh	Round		54569515200
Estradiol 0.05mg/day Patch	Tdp	Box	Flesh	Round		00378335099

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