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What is Cordarone I.v. (Amiodarone - Injection) ?

Can I buy Cordarone I.v. without Health Insurance, Medicare or Medicaid? Check and see if we carry Cordarone I.v. in our prescription list!

What Alternate Names Are There For Cordarone I.v.? Amiodarone Hcl

How is Cordarone I.v. (Amiodarone - Injection) Pronounced? am-ee-OH-duh-rown

Who is the Manufacturer of Cordarone I.v.? Wyeth Pharm

What is Cordarone I.v. Used For? Cordarone I.v. is used to treat irregular heart rhythms (arrhythmias) and to maintain a normal heart rate.

How To Use Cordarone I.v.
Cordarone I.v. is given by injection into a vein (IV) as directed by your doctor. Follow all instructions for proper mixing and dilution with the correct IV fluids. If you have questions regarding the use of Cordarone I.v., consult your pharmacist. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Do not exceed the recommended rate of infusion. Infusing amiodarone too fast may result in serious side effects such as severe lowering of the blood pressure. Your dosage and infusion rate may be adjusted depending upon your medical condition and response to therapy. A chemical (DEHP) found in plastic IV tubing may harm young children (male reproductive system effects). Amiodarone can cause this chemical to leach out of the tubing. Therefore, caution is advised when using Cordarone I.v. in children. Special administration guidelines should be followed (e.g., multiple bolus dosing) to minimize exposure to DEHP. Consult the pharmacist for more information.

Cordarone I.v. Side Effects
Also see the Warning section. Diarrhea, nausea, vomiting, or dizziness may occur. If any of these effects persist or worsen, notify your doctor promptly. Cordarone I.v., when used in combination with simvastatin, may infrequently cause muscle damage (which can rarely lead to a very serious condition called rhabdomyolysis). Tell your doctor immediately if you develop: muscle pain/tenderness/weakness (especially with fever or unusual tiredness). Tell your doctor immediately if any of these unlikely but serious side effects occur: severe dizziness, slowed heartbeat, uncontrolled shaking/tremor, unexplained weight gain, swelling of the hands or feet, irregular pulse, vision changes (e.g., seeing halos, blurred vision, loss of vision - See Warnings), easy bruising/bleeding, persistent sore throat. Cordarone I.v. may cause skin reactions similar to a serious sunburn. Infrequently with long-term amiodarone treatment, you may develop blue-gray discoloring of the skin, particularly of the face and hands. This effect is not harmful and usually reverses, sometimes incompletely, after Cordarone I.v. is stopped. Avoiding prolonged sun exposure may help to prevent this effect. See also Precautions. In the unlikely event you have an allergic reaction to Cordarone I.v., seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Cordarone I.v. Precautions
Cordarone I.v. should not be used if you have certain medical conditions. Before using Cordarone I.v., consult your doctor or pharmacist if you have: cardiogenic shock, certain types of irregular heartbeats or heart rhythms (e.g., severe sinus node dysfunction resulting in marked sinus bradycardia, second or third degree atrioventricular block, bradycardia with associated syncope except when a pacemaker is used). Before using Cordarone I.v., tell your doctor or pharmacist your medical history, especially of: liver disease, heart problems (e.g., congestive heart failure, low blood pressure), lung diseases, thyroid problems, upcoming major surgery, electrolyte problems such as low potassium or low magnesium, any allergies. Cordarone I.v. may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. Cordarone I.v. may make you more sensitive to the sun. Avoid prolonged sun exposure. Use a sunscreen and wear protective clothing when outdoors. Caution is advised when using Cordarone I.v. in the elderly because they may be more sensitive to the effects of Cordarone I.v., especially slowing of the heartbeat. A preservative (benzyl alcohol) which may be found in this product or in the liquid used to mix this product (diluent) can infrequently cause serious problems (sometimes death) if given by injection to an infant during the first months of life (neonatal period). The risk is greater with lower birth weight infants and is greater with increased amounts of benzyl alcohol. Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat. Report these symptoms to the doctor immediately should they occur. If possible, a preservative-free product should be used when treating neonates. Cordarone I.v. is not recommended for use during pregnancy due to the potential for fetal harm. Consult your doctor for more details. Amiodarone passes into breast milk. Breast-feeding is not recommended while using Cordarone I.v..

Cordarone I.v. Drug Interactions
Cordarone I.v. should not be used with the following medications because very serious interactions may occur: agalsidase beta, dofetilide, certain HIV protease inhibitors (nelfinavir, ritonavir), quinupristin/dalfopristin. If you are currently using any of these medications, tell your doctor or pharmacist before starting amiodarone. Other drugs besides amiodarone which may affect the heart rhythm (QTc prolongation in the EKG) include flecainide, disopyramide, pimozide, quinidine, sotalol, procainamide, and sparfloxacin among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for details. Ask for instructions about whether you need to stop any other QTc-prolonging drugs you may be using in order to minimize the risk of this effect. Before using Cordarone I.v., tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: blood thinners (e.g., warfarin), cimetidine, cyclosporine, digoxin, fentanyl, local and general anesthesia, heart medications (e.g., diltiazem, verapamil, beta-blockers such as propranolol), other HIV protease inhibitors (e.g., amprenavir, indinavir), methotrexate, phenytoin, rifampin, statins (e.g., lovastatin, simvastatin), St. John s wort. Do not start or stop any medicine without doctor or pharmacist approval.

Cordarone I.v. Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include weakness, severe dizziness, unusually slow heartbeat, or fainting.

Missed Cordarone I.v. Dose
If you miss a dose, contact the doctor immediately. Do not increase the rate of infusion above the recommended rate to catch up.

Cordarone I.v. Storage
Store at room temperature between 59 and 77 degrees F (15 and 25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Generic and Namebrand Variations
Label Name	Unit	Package	Color	Shape	Flavor	NDC
Amiodarone Hcl 50mg/ml Amp		Ampul				10019013101
Amiodarone Hcl 50mg/ml Amp	Ml	Ampul				00074434835
Amiodarone Hcl Ampul		Ampul				61703024103
Cordarone I.v. Ampul	Ml	Ampul	Yellow			00008081401

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