RENOVA
(tretinoin emollient cream 0.05%) contains the
same active ingredient as RETIN-A. It is a vitamin
A derivative like the one naturally occurring in your
body. But while RETIN-A is formulated for acne-prone
skin, RENOVA is a rich emollient cream developed
specifically for treating fine lines and wrinkles, brown
spots, surface roughness and stretch marks that develop
on the abdominal wall in women after pregnancy.
HOW
DOES RENOVA WORK?
RENOVA-A
works by binding to specific cell receptors of skin
after a topical application. After the cellular receptors
have been activated there is a modification in gene
expression, subsequent protein synthesis and cell growth
and differentiation. Thus, the epidermal cell is modified
to produce a greater amount of new mature healthy skin.
In clinical studies there is an enhanced production
of collagen in areas of treated skin.
Unlike
over-the-counter wrinkle creams that simply exfoliate
the surface layer of skin, RENOVA is believed
to work on all layers of the skin, including the epidermis,
where pigmentary changes occur and even the deeper portions
of the skin where fine wrinkling is thought to begin.
Medical research has shown in published articles that
RENOVA increases collagen. Researchers believe
this is one way that RENOVA reduces the signs
of aging.
HOW
EFFECTIVE IS RENOVA?
In
clinical studies looking at the efficacy of RENOVA
60% of patients treated for 24 weeks saw at least some
decrease in fine facial wrinkling. The effect on coarse
facial wrinkling, mottled hyperpigmentation, skin roughness,
and laxity of the facial skin were less clear since
the effect seen on each patient varied from study to
study.
A
study in the Archives of Dermatology, May 1996, showed
that RENOVA cream significantly improved the
appearance of early stretch marks. RENOVA worked
best on stretch marks that were new or enlarging, such
as those that develop during pregnancy.
HOW
TO USE THIS MEDICATION:
RENOVA
is for use on the face as directed, usually once a day
at bedtime. Apply a pea-size amount of cream to clean,
dry skin on the face being careful to avoid the eyes,
nostrils and mouth. Wash your hands after use. Do not
use this medication more often than prescribed or in
larger amounts. It will not give you faster or better
results but will increase the risk of side effects.
Do not use on sunburn or eczema or other serious skin
conditions. Effects of this medication will be gradual
with most improvement seen in the first 6 months of
continued therapy. If used for acne the condition may
worsen at first, and then improve.
RENOVA
TIMELINE:
1-2
months: you notice smoother skin and a softer texture
to your skin
3-4
months: freckles and brown spots begin to fade. Fine
lines and wrinkles begin to diminish. A rosier glow
to your skin is obtained
6
months: Benefits should be apparent with fewer wrinkles
and smoother and more even toned skin
DRUG
INTERACTIONS:
Let
us know on your medical history/personal profile of
any nonprescription or prescription medications that
you may be taking including isotretinoin, amiodarone,
tetracycline or quinolone antibiotics, sulfa drugs or
phenothiazines as they increase skin sensitivity to
the sun. Also let us know if you are using minoxidil
and any skin medication, soaps, cleansers, cosmetics,
astringents or any facial products that may be drying
or irritating to the skin (e.g., alcohol-containing
facial products). Benzoyl peroxide should not be applied
at the same time as this medication.
SIDE
EFFECTS:
You
may experience mild redness or stinging, itching, burning,
skin scaling, peeling and dry skin the first several
weeks as your body adjusts to RENOVA. If any
of these effects continue or become severe, discontinue
use.
WARNINGS:
Before
taking this medication let us know on your medical history/personal
profile if you have any pre-existing skin disorders
or if you have any allergies. This medication increases
your sensitivity to the sun. Limit sun exposure and
avoid sun lamps. Use a sunscreen and wear protective
clothing when outdoors. This medication should be used
only when clearly needed during pregnancy. It is unknown
if this drug is excreted into breast milk. Consult with
your doctor before breast-feeding.
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